The Blood Brain Barrier: Structure, Function, and Scientific Significance

Detailed 3D illustration of the blood brain barrier showing endothelial cells, tight junctions, astrocyte end-feet, and pericytes in a brain capillary

The blood–brain barrier (BBB) is a highly selective, semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system (CNS) where neurons reside .  This intricate cellular system is a critical component of neuroprotection, meticulously regulating the passage of substances to maintain the […]